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Psychiatry Grand Rounds

Imaging biomarkers of ECT response in major depression


Sep 3, 2014


10:30 - 12:00


Auditorium, Rachel Upjohn Building
4250 Plymouth Road
Ann Arbor, Michigan 


Katherine Narr, Ph.D.
Associate Professor-in-Residence, Departments of Neurology, Psychiatry and Biobehavioral Sciences, Geffen School of Medicine, University of California, Los Angeles

Dr. Katherine Narr is an Assistant Professor of Neurology and a faculty member within the Laboratory of Neuro Imaging at UCLA. Dr. Narr`s program of research is centered on using imaging data from multiple modalities, including proton magnetic resonance spectroscopy (1H MRS) and structural (sMRI), functional (fMRI) and diffusion tensor imaging (DTI), to facilitate a deeper understanding of the pathophysiological mechanisms and genetic contributions associated with schizophrenia and other psychiatric disorders. Though her work encompasses the study of structural and functional brain abnormalities across several different brain systems, she is focused on using advanced imaging methodologies to determine whether aspects of a specific cortical network, the medial temporal lobe (MTL) memory system, are selectively disturbed in schizophrenia. Specifically, experiments aim to establish the presence of structure-function relationships, and to identify system components indexing genetic vulnerability effects. She is also focused on addressing whether novel analysis strategies applied to 1H MRS data may determine whether disruptions of ongoing neurogenesis in the hippocampus and of the integration of new neurons into MTL and prefrontal cortical networks may be a mechanism by which schizophrenia develops. Other program goals include relating brain abnormalities identified using imaging methods to cognition, treatment response and functional outcome.

Faculty Disclosure:

CME Eligible: Yes

Live Webcast:
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